Articles

Advancing a cascading train-the-trainer model of frontline HIV service providers in South Africa: protocol of an implementation trial

South Africa is marked by high rates of both HIV and alcohol use, and there is a detrimental synergistic relationship between these two epidemics. The Institute of Medicine recommends integrated care for alcoh...

Authors: Caroline C. Kuo, Goodman Sibeko, Morayo Akande, Shaheema Allie, Nurain Tisaker, Dan J. Stein and Sara J. Becker

The relationship between opioid agonist therapy satisfaction and fentanyl exposure in a Canadian setting

While patient-reported treatment dissatisfaction is considered an important factor in determining the success of substance use disorder treatment, the levels of dissatisfaction with opioid agonist therapies (O...

Authors: Lindsay Mackay, Thomas Kerr, Nadia Fairbairn, Cameron Grant, M.-J. Milloy and Kanna Hayashi

Correction to: Adapting inpatient addiction medicine consult services during the COVID‑19 pandemic

An amendment to this paper has been published and can be accessed via the original article.

Authors: Miriam T. H. Harris, Alyssa Peterkin, Paxton Bach, Honora Englander, Emily Lapidus, Theresa Rolley, Melissa B. Weimer and Zoe M. Weinstein

Is telemedicine the answer to rural expansion of medication treatment for opioid use disorder? Early experiences in the feasibility study phase of a National Drug Abuse Treatment Clinical Trials Network Trial

Telemedicine (TM) enabled by digital health technologies to provide medical services has been considered a key solution to increasing health care access in rural communities. With the immediate need for remote...

Authors: Yih-Ing Hser, Allison J. Ober, Alex R. Dopp, Chunqing Lin, Katie P. Osterhage, Sarah E. Clingan, Larissa J. Mooney, Megan E. Curtis, Lisa A. Marsch, Bethany McLeman, Emily Hichborn, Laurie S. Lester, Laura-Mae Baldwin, Yanping Liu, Petra Jacobs and Andrew J. Saxon

Alcohol consumption and dependence is linked to the extent that people experience need satisfaction while drinking alcohol in two Aboriginal and Torres Strait Islander communities

Unhealthy alcohol use is a key concern for Aboriginal and Torres Strait Islander (‘Indigenous Australian’) communities. Due to systematic disadvantage and inter-generational trauma, Indigenous Australians may ...

Authors: James H. Conigrave, Emma L. Bradshaw, Katherine M. Conigrave, Richard M. Ryan, Scott Wilson, Jimmy Perry, Michael F. Doyle and K. S. Kylie Lee

Patient and provider knowledge of and attitudes toward medical conditions and medication during pregnancy

Knowledge of medical conditions and their evidence-based medications varies among individuals. This range of knowledge may affect attitudes and influence medical decision-making of both patients and providers....

Authors: Caroline Shadowen, Rachel Wheeler and Mishka Terplan

Should the CIWA-Ar be the standard monitoring strategy for alcohol withdrawal syndrome in the intensive care unit?

The Clinical Institute Withdrawal Assessment for Alcohol-Revised (CIWA-Ar) is commonly used in hospitals to titrate medications for alcohol withdrawal syndrome (AWS), but may be difficult to apply to intensive...

Authors: Tessa L. Steel, Shewit P. Giovanni, Sarah C. Katsandres, Shawn M. Cohen, Kevin B. Stephenson, Ben Murray, Hillary Sobeck, Catherine L. Hough, Katharine A. Bradley and Emily C. Williams

Integrating patient perspectives in the development of a mobile health intervention to address chronic pain and heavy drinking in primary care: a qualitative study of patients in an urban, safety-net hospital setting

Chronic pain and heavy drinking are conditions that commonly co-occur among primary care patients. Despite the availability of behavioral interventions that target these conditions individually, engagement and...

Authors: Tibor P. Palfai, Maya P. L. Kratzer, Natalia E. Morone and Judith A. Bernstein

External validation of an opioid misuse machine learning classifier in hospitalized adult patients

Opioid misuse screening in hospitals is resource-intensive and rarely done. Many hospitalized patients are never offered opioid treatment. An automated approach leveraging routinely captured electronic health ...

Authors: Majid Afshar, Brihat Sharma, Sameer Bhalla, Hale M. Thompson, Dmitriy Dligach, Randy A. Boley, Ekta Kishen, Alan Simmons, Kathryn Perticone and Niranjan S. Karnik

Motivational network intervention to reduce substance use and increase supportive connections among formerly homeless emerging adults transitioning to housing: study protocol for a pilot randomized controlled trial

Studies indicate high rates of substance use among youth experiencing homelessness (YEH). Further, the social networks of YEH, although multi-dimensional in composition, are largely comprised of other YEH, sub...

Authors: Joan S. Tucker, David P. Kennedy, Karen Chan Osilla and Daniela Golinelli

Integrating a brief alcohol intervention with tobacco addiction treatment in primary care: qualitative study of health care practitioner perceptions

Randomized trials of complex interventions are increasingly including qualitative components to further understand factors that contribute to their success. In this paper, we explore the experiences of health ...

Authors: Nadia Minian, Aliya Noormohamed, Mathangee Lingam, Laurie Zawertailo, Bernard Le Foll, Jürgen Rehm, Norman Giesbrecht, Andriy V. Samokhvalov, Dolly Baliunas and Peter Selby

Implementation facilitation to introduce and support emergency department-initiated buprenorphine for opioid use disorder in high need, low resource settings: protocol for multi-site implementation-feasibility study

For many reasons, the emergency department (ED) is a critical venue to initiate OUD interventions. The prevailing culture of the ED has been that substance use disorders are non-emergent conditions better addr...

Authors: Ryan P. McCormack, John Rotrosen, Phoebe Gauthier, Gail D’Onofrio, David A. Fiellin, Lisa A. Marsch, Patricia Novo, David Liu, E. Jennifer Edelman, Sarah Farkas, Abigail G. Matthews, Caroline Mulatya, Dagmar Salazar, Jeremy Wolff, Randolph Knight, William Goodman…

Prior National Drug Abuse Treatment Clinical Trials Network (CTN) opioid use disorder trials as background and rationale for NIDA CTN-0100 “optimizing retention, duration and discontinuation strategies for opioid use disorder pharmacotherapy (RDD)”

Opioid use disorder continues to be a significant problem in the United States and worldwide. Three medications—methadone, buprenorphine, and extended-release injectable naltrexone,— are efficacious for treati...

Authors: Matisyahu Shulman, Roger Weiss, John Rotrosen, Patricia Novo, Elizabeth Costello and Edward V. Nunes

Correction to: Proceedings of the Addiction Health Services Research (AHSR) 2020: Virtual Conference: Part 2

An amendment to this paper has been published and can be accessed via the original article.

Authors:

Adapting inpatient addiction medicine consult services during the COVID-19 pandemic

We describe addiction consult services (ACS) adaptations implemented during the Novel Coronavirus Disease 2019 (COVID-19) pandemic across four different North American sites: St. Paul’s Hospital in Vancouver, ...

Authors: Miriam T. H. Harris, Alyssa Peterkin, Paxton Bach, Honora Englander, Emily Lapidus, Theresa Rolley, Melissa B. Weimer and Zoe M. Weinstein

Creation of an algorithm for clinical decision support for treatment of opioid use disorder with buprenorphine in primary care

The treatment capacity for opioid use disorder (OUD) lags far behind the number of patients in need of treatment. Capacity is limited, in part, by the limited number of physicians who offer office based OUD tr...

Authors: Adriane M. dela Cruz, Robrina Walker, Ronny Pipes, Sidarth Wakhlu and Madhukar H. Trivedi

Comparing rapid micro-induction and standard induction of buprenorphine/naloxone for treatment of opioid use disorder: protocol for an open-label, parallel-group, superiority, randomized controlled trial

Buprenorphine/naloxone (Suboxone) is a current first-line treatment for opioid use disorder (OUD). The standard induction method of buprenorphine/naloxone requires patients to be abstinent from opioids and the...

Authors: James S. H. Wong, Mohammadali Nikoo, Jean N. Westenberg, Janet G. Suen, Jennifer Y. C. Wong, Reinhard M. Krausz, Christian G. Schütz, Marc Vogel, Jesse A. Sidhu, Jessica Moe, Shane Arishenkoff, Donald Griesdale, Nickie Mathew and Pouya Azar

Electronic cigarettes’ withdrawal severity symptoms among users during intermittent fasting: a cross-sectional study

Recently, electronic cigarette (e-cig) usage has increased significantly, making it a potentially effective smoking cessation tool. In Muslim countries, most people who use e-cigarettes fast the month of Ramad...

Authors: Muna M. Barakat, Raja’a A. Al-Qudah, Ibrahim Alfayoumi, Hala Jehad Al-Obaidi, Feras Jassim Jirjees and Iman Basheti

PRimary Care Opioid Use Disorders treatment (PROUD) trial protocol: a pragmatic, cluster-randomized implementation trial in primary care for opioid use disorder treatment

Most people with opioid use disorder (OUD) never receive treatment. Medication treatment of OUD in primary care is recommended as an approach to increase access to care. The PRimary Care Opioid Use Disorders t...

Authors: Cynthia I. Campbell, Andrew J. Saxon, Denise M. Boudreau, Paige D. Wartko, Jennifer F. Bobb, Amy K. Lee, Abigail G. Matthews, Jennifer McCormack, David S. Liu, Megan Addis, Andrea Altschuler, Jeffrey H. Samet, Colleen T. LaBelle, Julia Arnsten, Ryan M. Caldeiro, Douglas T. Borst…

“It’s way more than just writing a prescription”: A qualitative study of preferences for integrated versus non-integrated treatment models among individuals with opioid use disorder

Increasingly, treatment for opioid use disorder (OUD) is offered in integrated treatment models addressing both substance use and other health conditions within the same system. This often includes offering me...

Authors: Elizabeth C. Saunders, Sarah K. Moore, Olivia Walsh, Stephen A. Metcalf, Alan J. Budney, Patricia Cavazos-Rehg, Emily Scherer and Lisa A. Marsch

Information technology and addiction science: promises and challenges

Information technology can be used to advance addiction science and clinical practice.

Authors: Nicolas Bertholet and John A. Cunningham

The impact of project ECHO on physician preparedness to treat opioid use disorder: a systematic review

Opioid use disorder (OUD) is a medical condition that has evolved into a serious and deadly epidemic in the United States. Both medical and psychological interventions are called for to end this growing epidem...

Authors: Hunter M. Puckett, Jenny S. Bossaller and Lincoln R. Sheets

Multiple clinical risks for cannabis users during the COVID-19 pandemic

The pandemic caused by Sars-CoV-2 (COVID-19) has been a great concern for public and mental health systems worldwide. The identification of risk groups is essential for the establishment of preventive and ther...

Authors: Ellen Mello Borgonhi, Vanessa Loss Volpatto, Felipe Ornell, Francisco Diego Rabelo-da-Ponte and Felix Henrique Paim Kessler

Conceptualizing the effects of the COVID-19 pandemic on people with opioid use disorder: an application of the social ecological model

The COVID-19 pandemic has resulted in unparalleled societal disruption with wide ranging effects on individual liberties, the economy, and physical and mental health. While no social strata or population has b...

Authors: Ethan Cowan, Maria R. Khan, Siri Shastry and E. Jennifer Edelman

A novel brief treatment for methamphetamine use disorders in South Africa: a randomised feasibility trial

Effective brief treatments for methamphetamine use disorders (MAUD) are urgently needed to complement longer more intensive treatments in low and middle income countries, including South Africa. To address thi...

Authors: K. Sorsdahl, D. J. Stein, S. Pasche, Y. Jacobs, R. Kader, B. Odlaug, S. Richter, B. Myers and J. E. Grant

A Delphi yarn: applying Indigenous knowledges to enhance the cultural utility of SMART Recovery Australia

Mutual support groups are a popular treatment for substance use and other addictive behaviours. However, little is known about the cultural utility of these programmes for Indigenous peoples.

Authors: Elizabeth Dale, Katherine M. Conigrave, Peter J. Kelly, Rowena Ivers, Kathleen Clapham and K. S. Kylie Lee

Merging statewide data in a public/university collaboration to address opioid use disorder and overdose

Describe methods to compile a unified database from disparate state agency datasets linking person-level data on controlled substance prescribing, overdose, and treatment for opioid use disorder in Connecticut.

Authors: William C. Becker, Robert Heimer, Catherine M. Dormitzer, Molly Doernberg, Gail D’Onofrio, Lauretta E. Grau, Kathryn Hawk, Hsiu-Ju Lin, Alex M. Secora and David A. Fiellin

Proceedings of the Addiction Health Services Research (AHSR) 2020: Virtual Conference: Part 2

Authors:

Proceedings of the Addiction Health Services Research (AHSR) 2020 Virtual Conference: Part 1

Authors: Sara J. Becker

Addressing opioid use disorder among rural pregnant and postpartum women: a study protocol

Opioid use disorder (OUD) among women delivering at a hospital has increased 400% from 1999–2014 in the United States. From the years 2007 to 2016, opioid-related mortality during pregnancy increased over 200%...

Authors: M. Aryana Bryan, Marcela C. Smid, Melissa Cheng, Katherine T. Fortenberry, Amy Kenney, Bhanu Muniyappa, Danielle Pendergrass, Adam J. Gordon and Gerald Cochran

What is the prevalence of current alcohol dependence and how is it measured for Indigenous people in Australia, New Zealand, Canada and the United States of America? A systematic review

Alcohol affects Indigenous communities globally that have been colonised. These effects are physical, psychological, financial and cultural. This systematic review aims to describe the prevalence of current (1...

Authors: Teagan J. Weatherall, Katherine M. Conigrave, James H. Conigrave and K. S. Kylie Lee

What can primary care services do to help First Nations people with unhealthy alcohol use? A systematic review: Australia, New Zealand, USA and Canada

First Nations peoples of Australia, New Zealand, the United States of America (USA) and Canada are more likely to be non-drinkers than other people in these countries. However, those who do drink may be at gre...

Authors: Gemma C. Purcell-Khodr, K. S. Kylie Lee, James H. Conigrave, Emma Webster and Katherine M. Conigrave

Video directly observed therapy intervention using a mobile health application among opioid use disorder patients receiving office-based buprenorphine treatment: protocol for a pilot randomized controlled trial

Office-based buprenorphine treatment of opioid use disorder (OUD) does not typically include in-person directly observed therapy (DOT), potentially leading to non-adherence. Video DOT technologies may safeguar...

Authors: Zachery A. Schramm, Brian G. Leroux, Andrea C. Radick, Alicia S. Ventura, Jared W. Klein, Jeffrey H. Samet, Andrew J. Saxon, Theresa W. Kim and Judith I. Tsui

What constitutes “behavioral health”? Perceptions of substance-related problems and their treatment in primary care

Integrating behavioral health in primary care is a widespread endeavor. Yet rampant variation exists in models and approaches. One significant question is whether frontline providers perceive that behavioral h...

Authors: Ida Q. Chen, Helene Chokron Garneau, Timothy Seay-Morrison, Megan R. Mahoney, Heather Filipowicz and Mark P. McGovern

Integrated stepped alcohol treatment for patients with HIV and at-risk alcohol use: a randomized trial

At-risk levels of alcohol use threaten the health of patients with HIV (PWH), yet evidence-based strategies to decrease alcohol use and improve HIV-related outcomes in this population are lacking. We examined ...

Authors: E. Jennifer Edelman, Stephen A. Maisto, Nathan B. Hansen, Christopher J. Cutter, James Dziura, Yanhong Deng, Lynn E. Fiellin, Patrick G. O’Connor, Roger Bedimo, Cynthia L. Gibert, Vincent C. Marconi, David Rimland, Maria C. Rodriguez-Barradas, Michael S. Simberkoff, Janet P. Tate, Amy C. Justice…

Understanding the client characteristics of Aboriginal residential alcohol and other drug rehabilitation services in New South Wales, Australia

Aboriginal alcohol and other drug residential rehabilitation (residential rehabilitation) services have been providing treatment in Australia of over 50 years. However, there are no studies in Australia or int...

Authors: Douglas B. James, KS Kylie Lee, Tania Patrao, Ryan J. Courtney, Katherine M. Conigrave and Anthony Shakeshaft

Study protocol for a group-based motivational interviewing brief intervention to reduce substance use and sexual risk behavior among young adults experiencing homelessness

Young people experiencing homelessness have alarmingly high rates of alcohol and other drug (AOD) use, which is associated with sexual risk behaviors such as unprotected sex, trading sex, and sex with multiple...

Authors: Joan S. Tucker, Elizabeth J. D’Amico, Eric R. Pedersen, Anthony Rodriguez and Rick Garvey

Study design to evaluate a group-based therapy for support persons of adults on buprenorphine/naloxone

Opioid use disorders (OUDs) have devastating effects on individuals, families, and communities. While medication treatments for OUD save lives and are increasingly utilized, rates of treatment dropout are very...

Authors: Karen Chan Osilla, Kirsten Becker, Liisa Ecola, Brian Hurley, Jennifer K. Manuel, Allison Ober, Susan M. Paddock and Katherine E. Watkins

Assessing the readiness of digital data infrastructure for opioid use disorder research

Gaps in electronic health record (EHR) data collection and the paucity of standardized clinical data elements (CDEs) captured from electronic and digital data sources have impeded research efforts aimed at und...

Authors: Arjun Venkatesh, Caitlin Malicki, Kathryn Hawk, Gail D’Onofrio, Jeremiah Kinsman and Andrew Taylor

Chinese- and English-speaking adult current smokers’ perspectives on smoking and culturally and linguistically appropriate cessation: a qualitative analysis

A lack of culturally and linguistically appropriate smoking cessation intervention programs exist among Chinese-Canadian communities. Smoking cessation programs that are provided in Canadian mainstream culture...

Authors: Iraj Poureslami, Jessica Shum, Niloufar Aran and Noah Tregobov

Choosing internet-based treatment for problematic alcohol use—why, when and how? Users’ experiences of treatment online

Internet-based treatment has emerged as a cost-effective option for reaching people who for different reasons are not reached by traditional treatment. Internet-based treatment for problematic alcohol use, spe...

Authors: Veronica Ekström and Magnus Johansson

Commentary on substance use disorders and risk of suicide in a general US population: a case control study by Lynch et al.

In response to the findings of the Lynch et al. study on the association of suicide mortality and substance use disorder, this commentary addresses the need for increased suicide assessment and screening for p...

Authors: Virna Little and Mary Crawford James

How do state Medicaid programs determine what substance use disorder treatment medications need prior authorization? An overview for clinicians

The process by which state Medicaid programs develop their preferred drug lists, and determine which medications require prior authorization, is opaque to many clinicians. This process is a synthesis of cost a...

Authors: Marcus A. Bachhuber

Problem opioid use and HIV primary care engagement among hospitalized people who use drugs and/or alcohol

There is growing public health concern around the potential impact of the opioid crisis on efforts to eradicate HIV. This secondary analysis seeks to determine if those who report opioids as their primary prob...

Authors: Lacey Critchley, Adam Carrico, Natalie Gukasyan, Petra Jacobs, Raul N. Mandler, Allan E. Rodriguez, Carlos del Rio, Lisa R. Metsch and Daniel J. Feaster

One size doesn’t fit all: a thematic analysis of interviews with people who have stopped participating in Narcotics Anonymous in Norway

For persons with substance use disorders (SUDs), 12-step groups (TSGs) are the most available and used peer-based recovery resource, worldwide. However, disengagement is common, and attrition may partly be due...

Authors: John-Kåre Vederhus, Magnhild Høie and Bente Birkeland

Smartphone apps for managing alcohol consumption: a literature review

Smartphone applications (apps) designed to assist users to reduce hazardous and harmful alcohol consumption show potential as an inexpensive alternative to traditional brief intervention in primary care. The a...

Authors: Stephanie Colbert, Louise Thornton and Robyn Richmond

Development of an integrated digital health intervention to promote engagement in and adherence to medication for opioid use disorder

Buprenorphine-naloxone is an evidence-based treatment for Opioid Use Disorder. However, despite its efficacy, nearly half of participants are unsuccessful in achieving stabilization (i.e., period of time follo...

Authors: Kirsten J. Langdon, Susan Ramsey, Caroline Scherzer, Kate Carey, Megan L. Ranney and Josiah Rich

Health and economic outcomes of treatment with extended-release naltrexone among pre-release prisoners with opioid use disorder (HOPPER): protocol for an evaluation of two randomized effectiveness trials

Persons with an opioid use disorder (OUD) who were incarcerated face many challenges to remaining abstinent; concomitantly, opioid-overdose is the leading cause of death among this population, with the initial...

Authors: Sean M. Murphy, Philip J. Jeng, Sabrina A. Poole, Ali Jalali, Frank J. Vocci, Michael S. Gordon, George E. Woody and Daniel Polsky

Substance use disorders and risk of suicide in a general US population: a case control study

Prior research suggests that substance use disorders (SUDs) are associated with risk of suicide mortality, but most previous work has been conducted among Veterans Health Administration patients. Few studies h...

Authors: Frances L. Lynch, Edward L. Peterson, Christine Y. Lu, Yong Hu, Rebecca C. Rossom, Beth E. Waitzfelder, Ashli A. Owen-Smith, Samuel Hubley, Deepak Prabhakar, L. Keoki Williams, Arne Beck, Gregory E. Simon and Brian K. Ahmedani

Six-month retention and changes in quality of life and substance use from a low-threshold methadone maintenance therapy programme in Durban, South Africa

Emerging data points to a potential heroin use epidemic in South Africa. Despite this, access to methadone maintenance therapy and other evidence-based treatment options remains negligible. We aimed to assess ...

Authors: Andrew Scheibe, Shaun Shelly, Tara Gerardy, Zara von Homeyer, Andrea Schneider, Kalvanya Padayachee, Shalon Balaguru Naidoo, Klaas Mtshweni, Ayanda Matau, Harry Hausler and Monique Marks